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  2. Keyword: Atrial Fibrillation / therapy
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Editorial

Percutaneous Occlusion of Left Atrial Appendage: Growing Clinical Experience and Lack of Multicenter Randomized Clinical Trials

Cristiano F. Pisani et al. Mauricio Scanavacca

Left atrial appendage (LAA) closure as a prophylactic strategy for thromboembolic events in patients with atrial fibrillation (AF) has been performed for decades; initially during mitral valve repair surgeries and, more recently, in nonvalvular AF patients at high risk of embolism who do not tolerate the use of oral anticoagulants (OACs).

The idea of LAA occlusion as an alternative to chronic warfarin use emerged from observations of anatomopathological studies and during cardiac surgery that disclosed the LAA as the main site of thrombus formation in patients with nonvalvular atrial fibrillation.,

[…]

  • Atrial Appendage/diagnotic, imaging
  • Atrial Fibrillation / therapy
  • Prostheses and Implants/adverse effects
  • Stroke/prevention and control
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Creative Commons Attribution (CC BY) Creative Commons license
04/11/2019 DOI: 10.5935/abc.20190210 Views 2
Figure 1
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Case Report

Balloon Cryoablation for the Treatment of Paroxysmal Atrial Fibrillation

Guilherme Fenelon et al. Frederico Scuotto Claudio Fischer Marco Antonio Perin … Marcia Makdisse Angelo Amato Vincenzo de Paola

Introduction

Radiofrequency ablation (RFA) aiming at the electrical isolation of the pulmonary vein (PV) is more effective in controlling the rhythm than drugs, especially in young individuals with symptomatic paroxysmal atrial fibrillation (AF) without structural heart disease.– Electrical isolation is performed with point-by-point RFA around the PV, constituting a complex and lengthy procedure., Recently, technologies have been developed aiming to simplify PV isolation, among them the balloon cryoablation., In this approach, the cryoballoon is inflated in the PV ostium in order to completely occlude it. The release of cryoenergy cools the balloon surface, having the potential to isolate the vein with a single application. The efficacy and safety of cryoablation are similar to RFA, but the procedure is faster.–

Although used worldwide,– only recently cryoablation was made available in Brazil. The objective of this study was to report the first three cases performed in our country using this technology.

[…]

  • Atrial Fibrillation / therapy
  • Catheter Ablation/methods
  • Cryosurgery / methods
  • Cryosurgery / trends
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Creative Commons Attribution (CC BY) Creative Commons license
01/09/2017 DOI: 10.5935/abc.20170108

How to cite this article

EndNote RIS

Electronic Document Format (Vancouver)

Pisani CF, Scanavacca M. Percutaneous Occlusion of Left Atrial Appendage: Growing Clinical Experience and Lack of Multicenter Randomized Clinical Trials. Arquivos Brasileiros de Cardiologia 2019;113(4):722-4.

Electronic Document Format (ABNT)

Pisani, Cristiano F.; Scanavacca, Mauricio. Percutaneous Occlusion of Left Atrial Appendage: Growing Clinical Experience and Lack of Multicenter Randomized Clinical Trials. Arquivos Brasileiros de Cardiologia, v. 113, n. 4, p. 722-724, Nov. 2019.

Electronic Document Format (APA)

Pisani, C. F., & Scanavacca, M. (2019). Percutaneous Occlusion of Left Atrial Appendage: Growing Clinical Experience and Lack of Multicenter Randomized Clinical Trials. Arquivos Brasileiros de Cardiologia, 113(4), 722-724.

Electronic Document Format (ISO)

Pisani, Cristiano F. and Scanavacca, Mauricio. Percutaneous Occlusion of Left Atrial Appendage: Growing Clinical Experience and Lack of Multicenter Randomized Clinical Trials. Arquivos Brasileiros de Cardiologia [online]. 2019, vol. 113, n. 4, [cited 2026-10-14], pp. 722-724. Available from: <https://journals.cardiol.br/en/article/percutaneous-occlusion-of-left-atrial-appendage-growing-clinical-experience-and-lack-of-multicenter-randomized-clinical-trials/>. ISSN 0066-782X

EndNote RIS

Electronic Document Format (Vancouver)

Fenelon G, Scuotto F, Fischer C, Perin MA, Makdisse M, Paola AAV. Balloon Cryoablation for the Treatment of Paroxysmal Atrial Fibrillation. Arquivos Brasileiros de Cardiologia 2017;109(3):266-9.

Electronic Document Format (ABNT)

Fenelon, Guilherme; Scuotto, Frederico; Fischer, Claudio; Perin, Marco Antonio; Makdisse, Marcia; Paola, Angelo Amato Vincenzo de. Balloon Cryoablation for the Treatment of Paroxysmal Atrial Fibrillation. Arquivos Brasileiros de Cardiologia, v. 109, n. 3, p. 266-269, Aug. 2017.

Electronic Document Format (APA)

Fenelon, G., Scuotto, F., Fischer, C., Perin, M. A., Makdisse, M., & Paola, A. A. V. (2017). Balloon Cryoablation for the Treatment of Paroxysmal Atrial Fibrillation. Arquivos Brasileiros de Cardiologia, 109(3), 266-269.

Electronic Document Format (ISO)

Fenelon, Guilherme and Scuotto, Frederico and Fischer, Claudio and Perin, Marco Antonio and Makdisse, Marcia and Paola, Angelo Amato Vincenzo de. Balloon Cryoablation for the Treatment of Paroxysmal Atrial Fibrillation. Arquivos Brasileiros de Cardiologia [online]. 2017, vol. 109, n. 3, [cited 2026-10-14], pp. 266-269. Available from: <https://journals.cardiol.br/en/article/balloon-cryoablation-for-the-treatment-of-paroxysmal-atrial-fibrillation/>. ISSN 0066-782X

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