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  2. Keyword: animals, laboratory
Experimental myocardium infarction in rats: analysis of the model
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Review Article

Experimental myocardium infarction in rats: analysis of the model

Leonardo A. M. Zornoff et al. Sergio A. R. Paiva Marcos F. Minicucci Joel Spadaro

One of the most often used strategies to study the physiopathological alterations caused by coronary occlusion is the use of the experimental infarction model in rats. Among other factors, this is due to the similarities in the physiopathological alterations that occur after the infarction in humans. One must consider, however, that this model has characteristics that can hinder the use as well as the interpretation of eventual outcomes. Thus, this review aims at analyzing the main characteristics of the experimental infarction model in rats, discussing the coronary occlusion technique, the consequences and the methods of morphological and functional assessment of the infarction and its clinical implications.

  • animals, laboratory
  • Coronary Occlusion
  • Myocardial Infarction
  • Rats
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Creative Commons Attribution (CC BY) Creative Commons license
24/11/2009 DOI: 10.1590/S0066-782X2009001000018

How to cite this article

EndNote RIS

Electronic Document Format (Vancouver)

Zornoff LAM, Paiva SAR, Minicucci MF, Spadaro J. Experimental myocardium infarction in rats: analysis of the model. Arquivos Brasileiros de Cardiologia 2009;93(4):434-40.

Electronic Document Format (ABNT)

Zornoff, Leonardo A. M.; Paiva, Sergio A. R.; Minicucci, Marcos F.; Spadaro, Joel. Experimental myocardium infarction in rats: analysis of the model. Arquivos Brasileiros de Cardiologia, v. 93, n. 4, p. 434-440, Nov. 2009.

Electronic Document Format (APA)

Zornoff, L. A. M., Paiva, S. A. R., Minicucci, M. F., & Spadaro, J. (2009). Experimental myocardium infarction in rats: analysis of the model. Arquivos Brasileiros de Cardiologia, 93(4), 434-440.

Electronic Document Format (ISO)

Zornoff, Leonardo A. M. and Paiva, Sergio A. R. and Minicucci, Marcos F. and Spadaro, Joel. Experimental myocardium infarction in rats: analysis of the model. Arquivos Brasileiros de Cardiologia [online]. 2009, vol. 93, n. 4, [cited 2026-10-14], pp. 434-440. Available from: <https://journals.cardiol.br/en/article/experimental-myocardium-infarction-in-rats-analysis-of-the-model/>. ISSN 0066-782X

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