Ferhat Dindas et al. Emin Koyun Erdem Turkyilmaz Ozge Ozcan Abacioglu … Arafat Yildirim Anil Sahin Baris Dindar Mustafa Dogdus Ozkan Candan
Abstract
Background
The underlying pathology of isolated coronary artery ectasia (CE) has not been fully elucidated.
Objective
We aimed to examine the relationship between the systemic immune inflammation index (Sıı), which corresponds to the multiplying of the neutrophil-to-lymphocyte ratio (NLR) and the platelet counts, and isolated CE.
Method
The retrospective study population included 200 patients with isolated CE, 200 consecutive with obstructive coronary artery disease, and 200 consecutive with a normal coronary artery angiogram. A 2-sided p-value of <0.05 was considered significant.
Results
Sıı, NLR, platelet-to-lymphocyte ratio (PLR), and monocyte-to-high density lipoprotein cholesterol ratio (MHR) were significantly higher in the CE group compared with the other groups (all p<0.001). In multivariate analysis, Sıı (p517.35 has 79% sensitivity, 76% specificity for the prediction of the CE [AUC: 0.832, (p<0.001)]. Sıı had a significant correlation with the number of ectatic coronary arteries and Markis classification (r:0.214 p=0.002; r:-0.195, p=0.006, respectively).
Conclusion
To the best of our knowledge, this is the first study that Sıı was significantly associated with isolated CE presence and anatomical severity.