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Cost analysis of the treatment of acute decompensated heart failure: levosimendan versus dobutamine

Mucio Tavares Oliveira Jr et al. Wilson Follador Maria Lucia Orlandi Martins Roberta Canaviera … Rosana Lima Garcia Tsuji Airton Scipioni Antonio Carlos Pereira Barretto

OBJECTIVE: To assess whether the treatment with levosimendan is more expensive than the usual one with dobutamine, since price of medications does not usually represent the greatest expense in the treatment of cardiac decompensation. METHODS: The cost of treatment of 18 inpatients with cardiac decompensation, 9 of which treated with dobutamine (dobuta group) and 9 with levosimendan (levo group), was compared. Groups were similar concerning age, sex, functional class and cardiac function. RESULTS: Treatment costs were similar for both groups. In the levo group, the costs with the drug were higher than in the dobuta group, but those related to the length of stay in intensive care unit and to the material used during admission were lower. Levo – drug: R$ 5,414.00; material: R$ 399.90; hospital daily rates: R$ 5,061.20; professional honorarium: R$ 3,241.80; total costs: R$ 14,117.00. Dobuta – drug: R$ 2,320.10; materials: R$ 1,665.70; hospital daily rates: R$ 6,261.90; professional honorarium: R$ 3,894.30; total costs: R$ 14,142.00. CONCLUSION: Despite the higher price of levosimendan, the global cost of the treatment was similar for patients who were treated either with dobutamine or levosimendan. Patients who were treated with levosimendan had a shorter length of stay in intensive care unit.

  • decompensated heart failure
  • Dobutamine
  • inotropics
  • levosimendan
  • pharmacoeconomics
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Creative Commons Attribution (CC BY) Creative Commons license
29/09/2005 DOI: 10.1590/S0066-782X2005001400003

How to cite this article

EndNote RIS

Electronic Document Format (Vancouver)

Oliveira Jr MT, Follador W, Martins MLO, Canaviera R, Tsuji RLG, Scipioni A, Barretto ACP, et al. Cost analysis of the treatment of acute decompensated heart failure: levosimendan versus dobutamine. Arquivos Brasileiros de Cardiologia 2005;85(1):9-14.

Electronic Document Format (ABNT)

Oliveira Jr, Mucio Tavares; Follador, Wilson; Martins, Maria Lucia Orlandi; Canaviera, Roberta; Tsuji, Rosana Lima Garcia; Scipioni, Airton; Barretto, Antonio Carlos Pereira. Cost analysis of the treatment of acute decompensated heart failure: levosimendan versus dobutamine. Arquivos Brasileiros de Cardiologia, v. 85, n. 1, p. 9-14, Sep. 2005.

Electronic Document Format (APA)

Oliveira Jr, M. T., Follador, W., Martins, M. L. O., Canaviera, R., Tsuji, R. L. G., Scipioni, A., & Barretto, A. C. P. (2005). Cost analysis of the treatment of acute decompensated heart failure: levosimendan versus dobutamine. Arquivos Brasileiros de Cardiologia, 85(1), 9-14.

Electronic Document Format (ISO)

Oliveira Jr, Mucio Tavares and Follador, Wilson and Martins, Maria Lucia Orlandi and Canaviera, Roberta and Tsuji, Rosana Lima Garcia and Scipioni, Airton and Barretto, Antonio Carlos Pereira. Cost analysis of the treatment of acute decompensated heart failure: levosimendan versus dobutamine. Arquivos Brasileiros de Cardiologia [online]. 2005, vol. 85, n. 1, [cited 2026-10-14], pp. 9-14. Available from: <https://journals.cardiol.br/en/article/cost-analysis-of-the-treatment-of-acute-decompensated-heart-failure-levosimendan-versus-dobutamine/>. ISSN 0066-782X

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