Erika Correa Vrandecic et al. Ektor Correa Vrandecic Bayard Gontijo Filho Rossana Dall’Orto Elias … Braulio Roberto Gonçalves Marinho Couto Marcus Vinicius Bolivar Malachias
Heart valve disease currently occupies the spotlight in cardiovascular medicine due to recent advances in imaging techniques and emerging therapeutic possibilities, attracting the attention of physicians, researchers, device manufacturers, and investors. Brazil has a prominent international role in the history and technological development of prosthetic heart valves used to treat this disease.
The first worldwide implantation of a commercially available porcine valve bioprosthesis occurred in October 1968. About half a century later, in September 2019, passes on the physician and scientist Mario Vrandecic, creator of the only heart valve bioprosthesis made from porcine tissue produced in Brazil and approved by the United States (US) Food and Drug Administration (FDA), globally used for decades in the treatment of heart valve disease.
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