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  2. Keyword: Anaphylaxis
Figure 1
IJCS
Case Report

Allergy and Ischemia: A Case Report of Type II Kounis Syndrome

Rafael Viana et al. Miguel Carias Diogo Brás

Introduction

Kounis Syndrome (KS), also known as “allergic angina,” is a rare condition in which an allergic reaction triggers acute coronary events. Its mechanism involves mast cell degranulation, releasing inflammatory mediators such as histamine, cytokines, and proteases. These substances can induce coronary artery spasm, plaque rupture, or thrombus formation. KS is classified into three types: Type I (occurring in patients without coronary artery disease, CAD), Type II (in patients with pre-existing CAD), and Type III (associated with stent thrombosis). In this report, we present a case of Type II KS.

[…]

  • Acute coronary syndrome
  • Anaphylaxis
  • Kounis Syndrome
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Creative Commons Attribution (CC BY) Creative Commons license
03/08/2026 DOI: 10.36660/ijcs.20250037

How to cite this article

EndNote RIS

Electronic Document Format (Vancouver)

Viana R, Carias M, Brás D. Allergy and Ischemia: A Case Report of Type II Kounis Syndrome. International Journal of Cardiovascular Sciences 2026;39:e20250037.

Electronic Document Format (ABNT)

Viana, Rafael; Carias, Miguel; Brás, Diogo. Allergy and Ischemia: A Case Report of Type II Kounis Syndrome. International Journal of Cardiovascular Sciences, v. 39, e20250037, Aug. 2026.

Electronic Document Format (APA)

Viana, R., Carias, M., & Brás, D. (2026). Allergy and Ischemia: A Case Report of Type II Kounis Syndrome. International Journal of Cardiovascular Sciences, 39, e20250037.

Electronic Document Format (ISO)

Viana, Rafael and Carias, Miguel and Brás, Diogo. Allergy and Ischemia: A Case Report of Type II Kounis Syndrome. International Journal of Cardiovascular Sciences [online]. 2026, vol. 39, [cited 2026-10-14], e20250037. Available from: <https://journals.cardiol.br/en/article/allergy-and-ischemia-a-case-report-of-type-ii-kounis-syndrome/>. ISSN 2359-4802

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