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Família ABC

  • Família ABC
  • Arquivos Brasileiros de Cardiologia
  • International Journal of Cardiovascular Sciences
  • ABC Heart Failure & Cardiomyopathy
  • ABC Imagem Cardiovascular
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  2. Palavra-chave: ischemia
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Original Article

Surgical myocardial revascularization without extracorporeal circulation

Salomón Soriano Ordinola Rojas et al. Viviane C. Veiga Januario M. Souza Marcos S. Berlinck … José Alberto Iasbech Luiz Alberto Magna Reinaldo W. Vieira Sergio A. Oliveira

OBJECTIVE: To assess the immediate postoperative period of patients undergoing myocardial revascularization without extracorporeal circulation with different types of grafts. METHODS: One hundred and twelve patients, 89 (79.5%) of whom were males, were revascularized without extracorporeal circulation. Their ages ranged from 39 to 85 years. The criteria for indicating myocardial revascularization without extracorporeal circulation were as follows: revascularized coronary artery caliber > 1.5 mm, lack of intramyocardial trajectory on coronary angiography, noncalcified coronary arteries, and tolerance of the heart to the different rotation maneuvers. RESULTS: Myocardial revascularization without extracorporeal circulation was performed in 112 patients. Three were converted to extracorporeal circulation, which required a longer hospital stay but did not impact mortality. During the procedure, the following events were observed: atrial fibrillation in 10 patients, ventricular fibrillation in 4, total transient atrioventricular block in 2, ventricular extrasystoles in 58, use of a device to retrieve red blood cells in 53, blood transfusion in 8, and arterial hypotension in 89 patients. Coronary angiography was performed in 20 patients on the seventh postoperative day when the grafts were patent. CONCLUSION: Myocardial revascularization without extracorporeal circulation is a reproducible technique that is an alternative for treating ischemic heart disease.

  • Coronary Artery Disease
  • ischemia
  • Myocardial revascularization
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Creative Commons Attribution (CC BY) Creative Commons license
26/06/2003 DOI: 10.1590/S0066-782X2003000500003 Visualizações 1
ABC
Original Article

Effects of chlorthalidone and diltiazem on myocardial ischemia in elderly patients with hypertension and coronary artery disease

João Batista Serro-Azul et al. Rogério Silva de Paula César Gruppi Lígia Pinto … Humberto Pierri Amit Nussbacher Otávio Gebara Paulo Moffa Antônio Carlos Pereira-Barreto Maurício Wajngarten

OBJETIVE: Antihypertensive therapy with thiazides decreases coronary events in elderly patients. However, the influence of diuretics on myocardial ischemia has not been fully investigated. The aim of this study was to compare the effect of chlorthalidone and diltiazem on myocardial ischemia. METHODS: Following a randomized, double-blind, crossover protocol, we studied 15 elderly hypertensive patients aged 73.6±4.6 years with myocardial ischemia. All patients had angiographically documented coronary artery disease. We measured patients using 48- hour ambulatory electrocardiogram monitoring and exercise testing. After a 2-week period using placebo, patients received chlorthalidone or diltiazem for 4 weeks. RESULTS: Both treatments lowered systolic and diastolic blood pressures. The number of ischemic episodes on ambulatory electrocardiogram recordings was reduced with the use of chlorthalidone (2.5±3.8) and diltiazem (3.2±4.2) when compared with placebo (7.9±8.8; p<0.05). The total duration of ischemic episodes was reduced in both treatments when compared with placebo (chlorthalidone: 19.2±31.9min; diltiazem: 19.3±29.6min; placebo: 46.1±55.3min; p<0.05). CONCLUSION: In elderly hypertensive patients with coronary artery disease, chlorthalidone reduced myocardial ischemia similarly to diltiazem. This result is consistent with epidemiological studies and suggests that reduction of arterial blood pressure with thiazide therapy plays an important role in decreasing myocardial ischemia.

  • diuretics
  • Elderly
  • Hypertension
  • ischemia
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Creative Commons Attribution (CC BY) Creative Commons license
08/01/2002 DOI: 10.1590/S0066-782X2001000400001 Visualizações 2

Como citar este artigo

EndNote RIS

Formato de Documento Eletrônico (Vancouver)

Rojas SSO, Veiga VC, Souza JM, Berlinck MS, Iasbech JA, Magna LA, Vieira RW, et al. Surgical myocardial revascularization without extracorporeal circulation. Arquivos Brasileiros de Cardiologia 2003;80(5):502-8.

Formato de Documento Eletrônico (ABNT)

Rojas, Salomón Soriano Ordinola; Veiga, Viviane C.; Souza, Januario M.; Berlinck, Marcos S.; Iasbech, José Alberto; Magna, Luiz Alberto; Vieira, Reinaldo W.; Oliveira, Sergio A.. Surgical myocardial revascularization without extracorporeal circulation. Arquivos Brasileiros de Cardiologia, v. 80, n. 5, p. 502-508, jun. 2003.

Formato de Documento Eletrônico (APA)

Rojas, S. S. O., Veiga, V. C., Souza, J. M., Berlinck, M. S., Iasbech, J. A., Magna, L. A., Vieira, R. W., & Oliveira, S. A. (2003). Surgical myocardial revascularization without extracorporeal circulation. Arquivos Brasileiros de Cardiologia, 80(5), 502-508.

Formato de Documento Eletrônico (ISO)

Rojas, Salomón Soriano Ordinola and Veiga, Viviane C. and Souza, Januario M. and Berlinck, Marcos S. and Iasbech, José Alberto and Magna, Luiz Alberto and Vieira, Reinaldo W. and Oliveira, Sergio A.. Surgical myocardial revascularization without extracorporeal circulation. Arquivos Brasileiros de Cardiologia [online]. 2003, vol. 80, n. 5, [citado 2026-10-14], pp. 502-508. Disponível em: <https://journals.cardiol.br/article/surgical-myocardial-revascularization-without-extracorporeal-circulation-2/>. ISSN 0066-782X

EndNote RIS

Formato de Documento Eletrônico (Vancouver)

Serro-Azul JB, Paula RS, Gruppi C, Pinto L, Pierri H, Nussbacher A, Gebara O, et al. Effects of chlorthalidone and diltiazem on myocardial ischemia in elderly patients with hypertension and coronary artery disease. Arquivos Brasileiros de Cardiologia 2002;76(4):268-72.

Formato de Documento Eletrônico (ABNT)

Serro-Azul, João Batista; Paula, Rogério Silva de; Gruppi, César; Pinto, Lígia; Pierri, Humberto; Nussbacher, Amit; Gebara, Otávio; Moffa, Paulo; Pereira-Barreto, Antônio Carlos; Wajngarten, Maurício. Effects of chlorthalidone and diltiazem on myocardial ischemia in elderly patients with hypertension and coronary artery disease. Arquivos Brasileiros de Cardiologia, v. 76, n. 4, p. 268-272, jan. 2002.

Formato de Documento Eletrônico (APA)

Serro-Azul, J. B., Paula, R. S. , Gruppi, C., Pinto, L., Pierri, H., Nussbacher, A., Gebara, O., Moffa, P., Pereira-Barreto, A. C., & Wajngarten, M. (2002). Effects of chlorthalidone and diltiazem on myocardial ischemia in elderly patients with hypertension and coronary artery disease. Arquivos Brasileiros de Cardiologia, 76(4), 268-272.

Formato de Documento Eletrônico (ISO)

Serro-Azul, João Batista and Paula, Rogério Silva de and Gruppi, César and Pinto, Lígia and Pierri, Humberto and Nussbacher, Amit and Gebara, Otávio and Moffa, Paulo and Pereira-Barreto, Antônio Carlos and Wajngarten, Maurício. Effects of chlorthalidone and diltiazem on myocardial ischemia in elderly patients with hypertension and coronary artery disease. Arquivos Brasileiros de Cardiologia [online]. 2002, vol. 76, n. 4, [citado 2026-10-14], pp. 268-272. Disponível em: <https://journals.cardiol.br/article/effects-of-chlorthalidone-and-diltiazem-on-myocardial-ischemia-in-elderly-patients-with-hypertension-and-coronary-artery-disease-2/>. ISSN 0066-782X

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