Authors’ contributions
Research creation and design: Oliveira MB, Noriega AF, Miranda JR, Ricci GA, Ribeiro MBM, Oliveira MB, Murad Jr AJ. Data acquisition: Oliveira MB, Miranda JR, Ricci GA, Basaglia B, Oliveira MB, Murad Jr AJ. Data analysis and interpretation: Oliveira MB, Noriega AF, Ricci GA, Basaglia B, Ribeiro MBM, Oliveira MB, Murad Jr AJ. Statistical analysis: Noriega AF, Miranda JR, Ricci GA, Oliveira MB, Murad Jr AJ. Manuscript writing: Oliveira MB, Noriega AF, Miranda JR, Ricci GA, Basaglia B, Ribeiro MBM. Critical revision of the manuscript for important intellectual content: Oliveira MB, Noriega AF, Miranda JR, Ricci GA, Basaglia B, Ribeiro MBM, Oliveira MB, Murad Jr AJ.
Conflict of interest
The authors declare that there is no conflict of interest regarding this manuscript
Hypertrophic Cardiomyopathy (HCM) is a genetic disease that affects thousands of people around the world.
The present study aims to evaluate the presence of mitral regurgitation in patients with HCM, as well as its relationship with left ventricular Doppler echocardiographic variables. The mitral valve failure found in these patients is an extremely important finding, since it is able to predict the survival and mortality rate of the patients affected by HCM.
All echocardiograms performed from 2006 to 2016 in the echocardiographic service of Hospital de Base de São José do Rio Preto were evaluated. A total of 112,930 tests were gathered, of which those with HCM diagnosis or wall thickness >15 mm were selected and 132 patients were included in the analysis.
Moderate and major mitral valve regurgitation is present in 25% and 5.3% of the patients, respectively, and MRI is independently correlated with the obstructive form of HCM.
Mitral regurgitation is a frequent finding in patients with CMP, however, significant MI is extremely uncommon and is correlated with the obstructive form of the disease.
A cardiomiopatia hipertrófica é uma doença de origem genética, que afeta milhares de pessoas em todo o mundo.
Avaliar a presença de regurgitação mitral em pacientes com cardiomiopatia hipertrófica, bem como sua relação com variáveis ecodopplercardiográficas do ventrículo esquerdo. A disfunção de valva mitral encontradas nesses pacientes mostra-se um dado de extrema relevância, visto que é capaz de predizer a sobrevida e a taxa de mortalidade dos enfermos acometidos pela cardiomiopatia hipertrófica.
Foram avaliados todos os ecocardiogramas realizados no período de 2006 a 2016 no serviço de ecocardiografia do Hospital de Base de São José do Rio Preto, sendo o total de 112.930 exames. Foram selecionados aqueles com diagnóstico de cardiomiopatia hipertrófica ou espessura parietal > 15 mm, e incluídos na análise 132 pacientes. Resultados: Regurgitação valvar mitral de grau moderado e importante esteve presente em 25% e 5,3% dos pacientes, respectivamente, sendo que a regurgitação mitral esteve independentemente correlacionada com a forma obstrutiva de cardiomiopatia hipertrófica.
A regurgitação mitral é achado frequente em pacientes com cardiomiopatia hipertrófica, no entanto, a insuficiência mitral importante é extremamente incomum e está correlacionada com a forma obstrutiva da doença.