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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">dic</journal-id>
      <journal-title-group>
        <journal-title>Arquivos Brasileiros de Cardiologia Imagem cardiovascular</journal-title>
        
        <abbrev-journal-title abbrev-type="publisher">Arq Bras Cardiol: Imagem cardiovasc</abbrev-journal-title>
      </journal-title-group>
      <issn pub-type="epub">2675-312X</issn>
      <publisher>
        <publisher-name>Sociedade Brasileira de Cardiologia</publisher-name>
        
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">2318-8219.20180011</article-id>
      <article-id pub-id-type="doi">10.5935/2318-8219.20180011</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Original Article</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Association among Dyspnea and the Degrees of Diastolic Dysfunction at Echocardiography</article-title>
        <trans-title-group xml:lang="pt">
          <trans-title>Associação entre Dispneia e o Grau de Disfunção Diastólica ao Ecocardiograma</trans-title>
        </trans-title-group>
        <trans-title-group xml:lang="es">
          <trans-title>Asociación entre Disnea y el Grado de Disfunción Diastólica al Ecocardiograma</trans-title>
        </trans-title-group>
      </title-group>
      <contrib-group><contrib contrib-type="author"><name><surname>Passos</surname><given-names>Martha Beatriz de Souza Tavares</given-names></name><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Teixeira</surname><given-names>Isabelle Sasso</given-names></name><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Bortolon</surname><given-names>Paulo Henrique Botan Medeiros</given-names></name><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Beltrami</surname><given-names>Carlos Eduardo Carniel</given-names></name><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Camarozano</surname><given-names>Ana Cristina</given-names></name><xref ref-type="aff" rid="aff1"/></contrib></contrib-group>
      <aff id="aff1"><institution content-type="normalized"/><institution content-type="orgdiv1">Hospital de Clínicas</institution><institution content-type="orgname">Universidade Federal do Paraná</institution><addr-line><named-content content-type="city">Curitiba</named-content><named-content content-type="state">Paraná</named-content></addr-line><country country="BR">Brazil</country><institution content-type="original">Hospital de Clínicas da Universidade Federal do Paraná, Curitiba, Paraná - Brazil</institution></aff>
      <author-notes>
        <corresp id="c01"> Mailing Address: Martha Beatriz de Souza Tavares Passos • Hospital de Clínicas da Universidade Federal do Paraná R. Gen. Carneiro, 181. Postal Code 80060-900, Alto da Glória, Curitiba, PR – Brazil E-mail: <email>marthabia@gmail.com</email> </corresp>
        <fn fn-type="con">
	<p>Authors’ contributions</p>
	<p>Research creation and design: Teixeira IS, Passos MBST, Camarozano AC; Data acquisition: Teixeira IS, Passos MBST, Bortolon PHBM, Beltrami CEC, Camarozano AC; Data analysis and interpretation: Teixeira IS, Passos MBST, Bortolon PHBM, Beltrami CEC, Camarozano AC; Statistical analysis: Teixeira IS, Passos MBST, Camarozano AC; Manuscript drafting: Teixeira IS, Passos MBST; Critical revision of the manuscript for important intellectual content: Teixeira IS, Passos MBST, Camarozano AC.</p></fn><fn fn-type="conflict">
	<p>Potential Conflicts of Interest</p>
	<p>There are no relevant conflicts of interest.</p></fn>
      </author-notes>
      <pub-date date-type="pub" publication-format="electronic">
				<day>20</day>
				<month>01</month>
				<year>2022</year>
			</pub-date>
			<pub-date date-type="collection" publication-format="electronic">
        <season>Apr-Jun</season>
        <year>2018</year>
      </pub-date>
      <volume>31</volume>
      <issue>2</issue>
      <fpage>82</fpage>
      <lpage>89</lpage>
      <history><date date-type="received"><day>18</day><month>12</month><year>2017</year></date><date date-type="rev-recd"><day>14</day><month>01</month><year>2018</year></date><date date-type="accepted"><day>26</day><month>01</month><year>2018</year></date></history>
      <permissions>
<license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by-nc/3.0/">
<license-p>
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
</license-p>
</license>
</permissions>
      <abstract><title>Summary</title><sec><title>Introduction</title><p> The left ventricle diastolic dysfuntion (LVDD) can lead to heart failure with preserved ejection fraction. Echocardiography, especially the tissue Doppler, is the main exam. The clinic has dyspnea as a typical symptom, which is evaluated by modified Medical Research Council (mMRC). However, there are few studies that investigate what is the association between the symptom and LVDD.</p></sec><sec><title>Objective</title><p> Evaluate if dyspnea is associated with the advancement of LVDD and if there is a linkage between mMRC and the degrees of LVDD.</p></sec><sec><title>Method</title><p> Case-control transversal study, with 60 participants, with clinical (mMRC) and echocardiographic (bidimensional parameters, spectral and tissue Doppler) evaluation. Among the participants, 49 constituted the case group (LVDD with dyspnea) and 11 the control group (LVDD without dyspnea). Participants with co-morbidity or other echocardiographic abnormalities related to dyspnea were excluded.</p></sec><sec><title>Results</title><p> The average age was 61,7 (± 7,9) years and 72% were women. In overwall, 82% of the participants had dyspnea. Among them, 82% had LVDD degree I. All of the study population had preserved ventricular systolic function. The presence of dyspnea was associated with the degree of LVDD (p = 0,04), however, the symptom severity was not (p = 0,72).</p></sec><sec><title>Conclusion</title><p> Dyspnea was associated with the degree of LVDD, but there was no association between the symptom severity and the evolution of LVDD. The aging, the increase of left atrium and coronary artery disease were associated with the advanced grades of LVDD. (Arq Bras Cardiol: Imagem cardiovasc. 2018;31(2):82-89)</p></sec></abstract>
      <trans-abstract xml:lang="es"><title>Resumen</title><sec><title>Introducción</title><p> La disfunción diastólica del ventrículo izquierdo (DDVI) puede llevar a insuficiencia cardíaca con fracción de eyección preservada. El ecocardiograma, en especial el Doppler tisular, es el principal examen utilizado. La clínica generalmente cursa con disnea, evaluada por la escala modified Medical Research Council (mMRC). Entre tanto, existen pocos estudios que investiguen cual es la asociación entre el síntoma y la disfunción.</p></sec><sec><title>Objetivo</title><p> Evaluar si la queja de disnea se asocia con la progresión de la DDVI y si hay relación entre mMRC y los grados de DDVI.</p></sec><sec><title>Métodos</title><p> Estudio caso control y transversal, con 60 participantes, con evaluación clínica (mMRC) y ecocardiográfica (parámetros bidimensionales, Doppler espectral y tisular). Entre los participantes evaluados, 49 configuraron el grupo caso (DDVI con disnea) y 11 el grupo control (DDVI sin disnea). Fueron excluidos participantes con comorbilidades u otras alteraciones ecocardiográficas relacionadas a la disnea.</p></sec><sec><title>Resultados</title><p> La media de edad fue de 61,7 años (± 7,9), siendo 72% mujeres. Del total, 82% de los participantes presentaron disnea. De estos, 82% presentaron DDVI grado I. Todos presentaron función ventricular sistólica preservada. La presencia de disnea se asoció con el grado de DDVI (p = 0,04), relación que no se observó con la intensidad del síntoma (p = 0,72).</p></sec><sec><title>Conclusión</title><p> Hubo asociación entre la presencia de disnea y grado de DDVI, sin embargo no hubo relación entre la progresión de la disnea y la evolución de la DDVI. El aumento del atrio izquierdo y la presencia de enfermedad arterial coronaria fueron asociados con grados más avanzados de DDVI. (Arq Bras Cardiol: Imagem cardiovasc. 2018;31(2):82-89)</p></sec></trans-abstract>
      <trans-abstract xml:lang="pt"><title>Resumo</title><sec><title>Introdução</title><p> A disfunção diastólica do ventrículo esquerdo (DDVE) pode levar a insuficiência cardíaca com fração de ejeção preservada. O ecocardiograma, em especial o Doppler tecidual, é o principal exame utilizado. A clínica geralmente cursa com dispneia, avaliada pela escala modified Medical Research Council (mMRC). Entretanto, existem poucos estudos que investiguem qual é a associação entre o sintoma e a disfunção.</p></sec><sec><title>Objetivo</title><p> Avaliar se a queixa de dispneia se associa com a progressão da DDVE e se há relação entre mMRC e os graus de DDVE.</p></sec><sec><title>Métodos</title><p> Estudo caso-controle e transversal, com 60 participantes, com avaliação clínica (mMRC) e ecocardiográfica (parâmetros bidimensionais, Doppler espectral e tecidual). Dentre os participantes avaliados, 49 configuraram o grupo caso (DDVE com dispneia) e 11 o grupo controle (DDVE sem dispneia). Foram excluídos participantes com comorbidades ou outras alterações ecocardiográficas relacionadas à dispneia.</p></sec><sec><title>Resultados</title><p> A média de idade foi de 61,7 anos (± 7,9), sendo 72% mulheres. Do total, 82% dos participantes apresentaram dispneia. Destes, 82% apresentaram DDVE grau I. Todos apresentaram função ventricular sistólica preservada. A presença de dispneia se associou com o grau de DDVE (p = 0,04), relação que não se observou com a intensidade do sintoma (p = 0,72).</p></sec><sec><title>Conclusão</title><p> Houve associação entre a presença de dispneia e grau de DDVE, porém não houve relação entre a progressão da dispneia e a evolução da DDVE. O aumento do átrio esquerdo e a presença de doença arterial coronariana foram associadas com graus mais avançados de DDVE. (Arq Bras Cardiol: Imagem cardiovasc. 2018;31(2):89-96)</p></sec></trans-abstract>
      <kwd-group xml:lang="en"><kwd>Heart Failure</kwd><kwd>Stroke Volume</kwd><kwd>Dyspnea/complications</kwd><kwd>Ventricular Dysfunction</kwd><kwd>Echocardiography, Doppler</kwd></kwd-group>
      <kwd-group xml:lang="es"><kwd>Insuficiencia Cardíaca</kwd><kwd>Volumen Sistólico</kwd><kwd>Disnea/complicaciones</kwd><kwd>Disfunción Ventricular</kwd><kwd>Ecocardiografía Doppler</kwd></kwd-group>
      <kwd-group xml:lang="pt"><kwd>Insuficiência Cardíaca</kwd><kwd>Volume Sistólico</kwd><kwd>Dispneia/complicações</kwd><kwd>Disfunção Ventricular</kwd><kwd>Ecocardiografia Doppler</kwd></kwd-group>
      <counts><fig-count count="0"/><table-count count="0"/><equation-count count="0"/><ref-count count="0"/><page-count count="8"/></counts>
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