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  <front>
    <journal-meta>
      <journal-id journal-id-type="nlm-ta">Arq Bras Cardiol</journal-id>
      <journal-id journal-id-type="publisher-id">abc</journal-id>
      <journal-title-group>
        <journal-title>Arquivos Brasileiros de Cardiologia</journal-title>
        <abbrev-journal-title abbrev-type="publisher">Arq. Bras. Cardiol.</abbrev-journal-title>
      </journal-title-group>
      <issn pub-type="ppub">0066-782X</issn>
      <issn pub-type="epub">1678-4170</issn>
      <publisher>
        <publisher-name>Sociedade Brasileira de Cardiologia - SBC</publisher-name>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id specific-use="scielo-v3" pub-id-type="publisher-id">JMqFx9nXnkczHChPDRKhH9p</article-id>
      <article-id specific-use="scielo-v2" pub-id-type="publisher-id">S0066-782X2025000500902</article-id>
      <article-id pub-id-type="doi">10.36660/abc.20250078</article-id>
      <article-id pub-id-type="other">00902</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Carta ao Editor</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Como Comparar os Resultados Cl&#237;nicos entre a Crioabla&#231;&#227;o e a Abla&#231;&#227;o por Radiofrequ&#234;ncia em Pacientes com Taquicardia por Reentrada Nodal Atrioventricular?</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <name>
            <surname>Kataoka</surname>
            <given-names>Naoya</given-names>
          </name>
          <xref ref-type="aff" rid="aff1">
            <sup>1</sup>
          </xref>
          <xref ref-type="corresp" rid="c1"/>
        </contrib>
        <contrib contrib-type="author">
          <contrib-id contrib-id-type="orcid">0000-0002-7294-7637</contrib-id>
          <name>
            <surname>Imamura</surname>
            <given-names>Teruhiko</given-names>
          </name>
          <xref ref-type="aff" rid="aff1">
            <sup>1</sup>
          </xref>
        </contrib>
        <aff id="aff1">
          <label>1</label>
          <institution content-type="orgname">University of Toyama</institution>
          <addr-line>
            <named-content content-type="city">Toyama</named-content>
          </addr-line>
          <country country="JP">Jap&#227;o</country>
          <institution content-type="original">University of Toyama, Toyama &#8211; Jap&#227;o</institution>
        </aff>
      </contrib-group>
      <author-notes>
        <corresp id="c1"><label>Correspond&#234;ncia:</label><bold>Naoya Kataoka</bold> &#8226; University of Toyama - 2630 Sugitani, <postal-code>930-0194</postal-code>, Toyama &#8211; Jap&#227;o E-mail: <email>nkataoka@icloud.com</email> </corresp>
      </author-notes>
      <pub-date date-type="pub" publication-format="electronic">
        <day>16</day>
        <month>06</month>
        <year>2025</year>
      </pub-date>
      <pub-date date-type="collection" publication-format="electronic">
        <year>2025</year>
      </pub-date>
      <volume>122</volume>
      <issue>5</issue>
      <elocation-id>e20250078</elocation-id>
      <history>
        <date date-type="received">
          <day>03</day>
          <month>02</month>
          <year>2025</year>
        </date>
        <date date-type="rev-recd">
          <day>05</day>
          <month>02</month>
          <year>2025</year>
        </date>
        <date date-type="accepted">
          <day>05</day>
          <month>02</month>
          <year>2025</year>
        </date>
      </history>
      <permissions>
        <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/" xml:lang="en">
          <license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution License</license-p>
        </license>
      </permissions>
      <kwd-group xml:lang="pt">
        <title>Palavras-chave</title>
        <kwd>Taquicardia</kwd>
        <kwd>Criocirurgia</kwd>
        <kwd>Abla&#231;&#227;o por Radiofrequ&#234;ncia</kwd>
      </kwd-group>
      <counts>
        <fig-count count="0"/>
        <table-count count="0"/>
        <equation-count count="0"/>
        <ref-count count="3"/>
      </counts>
    </article-meta>
  </front>
  <body>
    <p>
      <bold>Ao Editor</bold>
    </p>
    <p>A abla&#231;&#227;o de taquicardia de reentrada nodal atrioventricular (TRNAV) usando crioabla&#231;&#227;o surgiu como uma alternativa vi&#225;vel &#224; abla&#231;&#227;o por radiofrequ&#234;ncia (RF) devido ao seu risco reduzido de induzir bloqueio atrioventricular permanente. No entanto, essa t&#233;cnica necessita de considera&#231;&#245;es processuais espec&#237;ficas para minimizar a recorr&#234;ncia de arritmias. Os autores conduziram uma an&#225;lise comparativa dos resultados cl&#237;nicos entre a crioabla&#231;&#227;o e a abla&#231;&#227;o por RF convencional, demonstrando que a crioabla&#231;&#227;o foi associada &#224; redu&#231;&#227;o do tempo de fluoroscopia e n&#227;o foi inferior &#224; abla&#231;&#227;o por RF em termos de efic&#225;cia e viabilidade processual para o tratamento de TRNAV.<sup><xref ref-type="bibr" rid="B1">1</xref></sup> No entanto, v&#225;rias preocupa&#231;&#245;es cr&#237;ticas merecem discuss&#227;o adicional.</p>
    <p>Na compara&#231;&#227;o das caracter&#237;sticas basais, os intervalos &#225;trio-his e his-ventricular foram observados como sendo maiores na coorte de crioabla&#231;&#227;o.<sup><xref ref-type="bibr" rid="B1">1</xref></sup> Isso levanta a possibilidade de que pacientes com intervalos PR basais prolongados foram selecionados preferencialmente para crioabla&#231;&#227;o a fim de mitigar o risco de dist&#250;rbios de condu&#231;&#227;o atriovenricular p&#243;s-procedimento. Se esse vi&#233;s de sele&#231;&#227;o influenciou os resultados do estudo, ele deve ser reconhecido e explorado na discuss&#227;o.</p>
    <p>O significado cl&#237;nico do per&#237;odo refrat&#225;rio efetivo do n&#243; atriovenricular (PRENAV) permanece amb&#237;guo. Se o PRENAV reflete o per&#237;odo refrat&#225;rio da via r&#225;pida, ent&#227;o a crioabla&#231;&#227;o parece exercer um impacto maior na condu&#231;&#227;o da via r&#225;pida em compara&#231;&#227;o &#224; abla&#231;&#227;o por RF. Por outro lado, se o PRENAV representa a via lenta, &#233; prov&#225;vel que seja influenciado pela infus&#227;o de isoproterenol administrada durante o procedimento, o que pode alterar a interpreta&#231;&#227;o dos resultados.</p>
    <p>Ao contr&#225;rio da abla&#231;&#227;o por RF, cujo local de tratamento &#233; guiado por marcos anat&#244;micos, a crioabla&#231;&#227;o frequentemente apresenta desafios na localiza&#231;&#227;o precisa do local terap&#234;utico ideal. Os autores empregaram sistemas de mapeamento tridimensional recentemente inovados para identificar as zonas de abla&#231;&#227;o alvo para a crioabla&#231;&#227;o precisamente?<sup><xref ref-type="bibr" rid="B2">2</xref>,<xref ref-type="bibr" rid="B3">3</xref></sup> Este ponto &#233; particularmente significativo, dado que tr&#234;s pacientes apresentaram arritmias recorrentes ap&#243;s o procedimento.</p>
  </body>
  <back>
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          <article-title>Ablation of Atrioventricular Nodal Reentrant Tachycardia with Focal Cryoablation, Compared with Radiofrequency Ablation: Single-Center Experience</article-title>
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  </back>
  <sub-article article-type="translation" id="s1" xml:lang="en">
    <front-stub>
      <article-id pub-id-type="doi">10.36660/abc.20250078i</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Letter to the Editor</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>How to Compare Clinical Outcomes between Cryoablation and Radiofrequency Ablation in Patients with Atrioventricular Nodal Reentrant Tachycardia?</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <name>
            <surname>Kataoka</surname>
            <given-names>Naoya</given-names>
          </name>
          <xref ref-type="aff" rid="aff2">
            <sup>1</sup>
          </xref>
          <xref ref-type="corresp" rid="c2"/>
        </contrib>
        <contrib contrib-type="author">
          <contrib-id contrib-id-type="orcid">0000-0002-7294-7637</contrib-id>
          <name>
            <surname>Imamura</surname>
            <given-names>Teruhiko</given-names>
          </name>
          <xref ref-type="aff" rid="aff2">
            <sup>1</sup>
          </xref>
        </contrib>
        <aff id="aff2">
          <label>1</label>
          <institution content-type="orgname">University of Toyama</institution>
          <addr-line>
            <named-content content-type="city">Toyama</named-content>
          </addr-line>
          <country country="JP">Japan</country>
          <institution content-type="original">University of Toyama, Toyama &#8211; Japan</institution>
        </aff>
      </contrib-group>
      <author-notes>
        <corresp id="c2"><label>Mailing Address:</label><bold>Naoya Kataoka</bold> &#8226; University of Toyama - 2630 Sugitani, <postal-code>930-0194</postal-code>, Toyama &#8211; Japan E-mail: <email>nkataoka@icloud.com</email> </corresp>
      </author-notes>
      <kwd-group xml:lang="en">
        <title>Keywords</title>
        <kwd>Tachycardia</kwd>
        <kwd>Cryosurgery</kwd>
        <kwd>Radiofrequency Ablation</kwd>
      </kwd-group>
    </front-stub>
    <body>
      <p>
        <bold>To Editor</bold>
      </p>
      <p>The ablation of atrioventricular nodal reentrant tachycardia (AVNRT) using cryoablation has emerged as a viable alternative to radiofrequency (RF) ablation due to its reduced risk of inducing permanent atrioventricular block. However, this technique necessitates specific procedural considerations to minimize the recurrence of arrhythmias. The authors conducted a comparative analysis of clinical outcomes between cryoablation and conventional RF ablation, demonstrating that cryoablation was associated with reduced fluoroscopy time and was non-inferior to RF ablation in terms of efficacy and procedural feasibility for AVNRT management.<sup><xref ref-type="bibr" rid="B1">1</xref></sup> Nonetheless, several critical concerns merit further discussion.</p>
      <p>In the comparison of baseline characteristics, atrium-his and his-ventricular intervals were observed to be longer in the cryoablation cohort.<sup><xref ref-type="bibr" rid="B1">1</xref></sup> This raises the possibility that patients with prolonged baseline PR intervals were preferentially selected for cryoablation in order to mitigate the risk of post-procedural atrioventricular conduction disorders. If this selection bias influenced the study's outcomes, it should be acknowledged and explored in the discussion.</p>
      <p>The clinical significance of the atrioventricular node effective refractory period (AVNER) remains ambiguous. If AVNER reflects the refractory period of the fast pathway, then cryoablation appears to exert a greater impact on fast pathway conduction compared to RF ablation. Conversely, if AVNER represents the slow pathway, it is likely influenced by the isoproterenol infusion administered during the procedure, which could alter the interpretation of results.</p>
      <p>Unlike RF ablation, whose treatment site is guided by anatomical landmarks, cryoablation often poses challenges in accurately localizing the optimal therapeutic site. Did the authors employ recently innovated three-dimensional mapping systems to identify the target ablation zones for cryoablation precisely?<sup><xref ref-type="bibr" rid="B2">2</xref>,<xref ref-type="bibr" rid="B3">3</xref></sup> This point is particularly significant given that three patients experienced recurrent arrhythmias following the procedure.</p>
    </body>
  </sub-article>
</article>
