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  <front>
    <journal-meta>
      <journal-id journal-id-type="nlm-ta">Arq Bras Cardiol</journal-id>
      <journal-id journal-id-type="publisher-id">abc</journal-id>
      <journal-title-group>
        <journal-title>Arquivos Brasileiros de Cardiologia</journal-title>
        <abbrev-journal-title abbrev-type="publisher">Arq. Bras. Cardiol.</abbrev-journal-title>
      </journal-title-group>
      <issn pub-type="ppub">0066-782X</issn>
      <issn pub-type="epub">1678-4170</issn>
      <publisher>
        <publisher-name>Sociedade Brasileira de Cardiologia - SBC</publisher-name>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id" specific-use="scielo-v3">hZczYywqXckBrjcjckXcLQf</article-id>
      <article-id pub-id-type="publisher-id" specific-use="scielo-v2">S0066-782X2020000701076</article-id>
      <article-id pub-id-type="publisher-id">abc.20200081</article-id>
      <article-id pub-id-type="doi">10.36660/abc.20200081</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Imagem</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Altera&#231;&#245;es Eletrocardiogr&#225;ficas Induzidas pela Hipotermia</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <contrib-id contrib-id-type="orcid">0000-0001-8341-6412</contrib-id>
          <name>
            <surname>Marques</surname>
            <given-names>Ana</given-names>
          </name>
          <xref ref-type="aff" rid="aff1">
            <sup>1</sup>
          </xref>
        </contrib>
        <contrib contrib-type="author">
          <contrib-id contrib-id-type="orcid">0000-0002-2520-5673</contrib-id>
          <name>
            <surname>Caldeira</surname>
            <given-names>Daniel</given-names>
          </name>
          <xref ref-type="aff" rid="aff2">
            <sup>2</sup>
          </xref>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Briosa</surname>
            <given-names>Alexandra</given-names>
          </name>
          <xref ref-type="aff" rid="aff1">
            <sup>1</sup>
          </xref>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Jo&#227;o</surname>
            <given-names>Isabel</given-names>
          </name>
          <xref ref-type="aff" rid="aff1">
            <sup>1</sup>
          </xref>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Pereira</surname>
            <given-names>H&#233;lder</given-names>
          </name>
          <xref ref-type="aff" rid="aff1">
            <sup>1</sup>
          </xref>
        </contrib>
      </contrib-group>
      <aff id="aff1">
        <label>1</label>
        <institution content-type="orgname">Hospital Garcia de Orta EPE</institution>
        <addr-line>
          <named-content content-type="city">Almada</named-content>
        </addr-line>
        <country country="PT">Portugal</country>
        <institution content-type="original">Hospital Garcia de Orta EPE,Almada - Portugal</institution>
      </aff>
      <aff id="aff2">
        <institution content-type="orgdiv2">Centro Cardiovascular</institution>
        <institution content-type="orgdiv1">Faculdade Medicina</institution>
        <institution content-type="orgname">Universidade de Lisboa</institution>
        <addr-line>
          <named-content content-type="city">Lisboa</named-content>
        </addr-line>
        <country country="PT">Portugal</country>
        <institution content-type="original">Centro Cardiovascular da Universidade de Lisboa - CCUL, Laborat&#243;rio de Farmacologia Cl&#237;nica e Terap&#234;utica, Faculdade Medicina, Universidade de Lisboa, Lisboa - Portugal</institution>
      </aff>
      <author-notes>
        <corresp id="c01"> Correspond&#234;ncia: Ana Marques &#8226; Hospital Garcia de Orta EPE &#8211; Av. Torrado da Silva, 2801-951, Almada &#8211; Portugal E-mail: <email>ana.smc.25@gmail.com</email>
				</corresp>
      </author-notes>
      <pub-date date-type="pub" publication-format="electronic">
        <day>03</day>
        <month>07</month>
        <year>2020</year>
      </pub-date>
      <pub-date date-type="collection" publication-format="electronic">
        <month>06</month>
        <year>2020</year>
      </pub-date>
      <volume>114</volume>
      <issue>6</issue>
      <fpage>1076</fpage>
      <lpage>1077</lpage>
      <history>
        <date date-type="received">
          <day>11</day>
          <month>02</month>
          <year>2020</year>
        </date>
        <date date-type="rev-recd">
          <day>22</day>
          <month>03</month>
          <year>2020</year>
        </date>
        <date date-type="accepted">
          <day>22</day>
          <month>03</month>
          <year>2020</year>
        </date>
      </history>
      <permissions>
        <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/" xml:lang="en">
          <license-p> This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. </license-p>
        </license>
      </permissions>
      <kwd-group xml:lang="pt">
        <kwd>Bradicardia</kwd>
        <kwd>Bloqueio Atrioventricular</kwd>
        <kwd>Eletrocardiografia/m&#233;todos</kwd>
        <kwd>Hipotermia</kwd>
        <kwd>Ondas Osborn</kwd>
      </kwd-group>
      <counts>
        <fig-count count="2"/>
        <table-count count="0"/>
        <equation-count count="0"/>
        <ref-count count="2"/>
        <page-count count="2"/>
      </counts>
    </article-meta>
  </front>
  <body>
    <p>Uma paciente idosa foi levada ao pronto-socorro devido &#224; perda de consci&#234;ncia. Apresentava antecedentes pessoais de hipercolesterolemia e hipertens&#227;o essencial. A paciente n&#227;o era tratada com nenhum medicamento cronotr&#243;pico negativo. Na hospitaliza&#231;&#227;o, a press&#227;o arterial da paciente era de 90/60 mmHg, ela apresentava bradicardia (42 bat./minuto) e hipotermia (33&#186;C). O eletrocardiograma (ECG) mostrou bradicardia sinusal, bloqueio atrioventricular de 1&#186; grau, prolongamento do intervalo QT corrigido e ondas de Osborn ao final dos complexos QRS ( <xref ref-type="fig" rid="f01">Figura 1 A</xref> , pontas de seta). Dessa forma, essas deflex&#245;es positivas de entalhe foram melhor observadas nas deriva&#231;&#245;es precordiais laterais e desapareceram ap&#243;s o aquecimento da paciente a 36&#186;C ( <xref ref-type="fig" rid="f01">Figura 1 B</xref> ). A bradicardia, o bloqueio atrioventricular e prolongamento do QT tamb&#233;m foram resolvidos ( <xref ref-type="fig" rid="f01">Figura 1 B</xref> ). Durante a interna&#231;&#227;o, a tomografia computadorizada da cabe&#231;a, o Holter de 24 horas e a an&#225;lise laboratorial n&#227;o revelaram altera&#231;&#245;es significativas. O ecocardiograma transtor&#225;cico revelou apenas altera&#231;&#245;es degenerativas das v&#225;lvulas a&#243;rtica e mitral. Este caso &#233; ilustrativo de altera&#231;&#245;es eletrocardiogr&#225;ficas induzidas por hipotermia, especificamente, prolongamento dos intervalos PR, RR e QT e, principalmente, a presen&#231;a de ondas de Osborn.<sup><xref ref-type="bibr" rid="B1">1</xref> , <xref ref-type="bibr" rid="B2">2</xref></sup></p>
    <p>
      <fig id="f01">
        <label>Figura 1</label>
        <caption>
          <title>
            <italic>Painel A) Eletrocardiograma (ECG) mostrando altera&#231;&#245;es de ECG induzidas por hipotermia: bradicardia sinusal, bloqueio atrioventricular de 1&#186; grau, pronlongamento do intervalo QT corrigido e ondas de Osborn no final dos complexos QRS (pontas de seta). Painel B) Ap&#243;s o aquecimento da paciente, o eletrocardiograma (ECG) mostra resolu&#231;&#227;o das altera&#231;&#245;es eletrocardiogr&#225;ficas induzidas por hipotermia.</italic>
          </title>
        </caption>
        <graphic xlink:href="1678-4170-abc-114-06-1076-00081-gf01.jpg"/></fig>
    </p>
  </body>
  <back>
    <ref-list>
      <title>Refer&#234;ncias</title>
      <ref id="B1">
        <label>1</label>
        <mixed-citation>1. Alhaddad IA, Khalil M, Brown EJ Jr. Osborn waves of hypothermia. Circulation. 2000;101(25):E233-E244.</mixed-citation>
        <element-citation publication-type="journal">
          <person-group person-group-type="author">
            <name>
              <surname>Alhaddad</surname>
              <given-names>IA</given-names>
            </name>
            <name>
              <surname>Khalil</surname>
              <given-names>M</given-names>
            </name>
            <name>
              <surname>Brown</surname>
              <given-names>EJ</given-names>
              <suffix>Jr</suffix>
            </name>
          </person-group>
          <article-title>Osborn waves of hypothermia</article-title>
          <source>Circulation</source>
          <year>2000</year>
          <volume>101</volume>
          <issue>25</issue>
        </element-citation>
      </ref>
      <ref id="B2">
        <label>2</label>
        <mixed-citation>2. Doshi HH, Giudici MC. The EKG in hypothermia and hyperthermia. J Electrocardiol 2015; 48(2):203&#8211;8.</mixed-citation>
        <element-citation publication-type="journal">
          <person-group person-group-type="author">
            <name>
              <surname>Doshi</surname>
              <given-names>HH</given-names>
            </name>
            <name>
              <surname>Giudici</surname>
              <given-names>MC</given-names>
            </name>
          </person-group>
          <article-title>The EKG in hypothermia and hyperthermia</article-title>
          <source>J Electrocardiol</source>
          <year>2015</year>
          <volume>48</volume>
          <issue>2</issue>
          <fpage>203</fpage>
        </element-citation>
      </ref>
    </ref-list>
  </back>
  <sub-article article-type="translation" id="TRen" xml:lang="en">
    <front-stub>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Image</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Hypothermia-Induced Electrocardiographic Changes</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <contrib-id contrib-id-type="orcid">0000-0001-8341-6412</contrib-id>
          <name>
            <surname>Marques</surname>
            <given-names>Ana</given-names>
          </name>
          <xref ref-type="aff" rid="aff1001">
            <sup>1</sup>
          </xref>
        </contrib>
        <contrib contrib-type="author">
          <contrib-id contrib-id-type="orcid">0000-0002-2520-5673</contrib-id>
          <name>
            <surname>Caldeira</surname>
            <given-names>Daniel</given-names>
          </name>
          <xref ref-type="aff" rid="aff2001">
            <sup>2</sup>
          </xref>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Briosa</surname>
            <given-names>Alexandra</given-names>
          </name>
          <xref ref-type="aff" rid="aff1001">
            <sup>1</sup>
          </xref>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Jo&#227;o</surname>
            <given-names>Isabel</given-names>
          </name>
          <xref ref-type="aff" rid="aff1001">
            <sup>1</sup>
          </xref>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Pereira</surname>
            <given-names>H&#233;lder</given-names>
          </name>
          <xref ref-type="aff" rid="aff1001">
            <sup>1</sup>
          </xref>
        </contrib>
      </contrib-group>
      <aff id="aff1001">
        <label>1</label>
        <country country="PT">Portugal</country>
        <institution content-type="original">Hospital Garcia de Orta EPE, Almada - Portugal</institution>
      </aff>
      <aff id="aff2001">
        <country country="PT">Portugal</country>
        <institution content-type="original">Centro Cardiovascular da Universidade de Lisboa - CCUL, Laborat&#243;rio de Farmacologia Cl&#237;nica e Terap&#234;utica, Faculdade Medicina, Universidade de Lisboa, Lisboa - Portugal</institution>
      </aff>
      <author-notes>
        <corresp id="c01001">Mailing Address: Ana Marques &#8226; Hospital Garcia de Orta EPE &#8211; Av. Torrado da Silva, 2801-951, Almada &#8211; Portugal E-mail: ana.smc.25@gmail.com</corresp>
      </author-notes>
      <kwd-group xml:lang="en">
        <kwd>Bradycardia</kwd>
        <kwd>Atrioventricular Block</kwd>
        <kwd>Electrocardiography/methods</kwd>
        <kwd>Hypothermia</kwd>
        <kwd>Osborn Waves</kwd>
      </kwd-group>
    </front-stub>
    <body>
      <p>An elderly female patient was brought to the Emergency Department due to loss of consciousness. The past medical history was remarkable for hypercholesterolemia and essential hypertension. The patient was not treated with any negative chronotropic drug. At the admission, the patient&#8217;s blood pressure was 90/60 mmHg, she had bradycardia (42/minute), and hypothermia (33&#186;C). Electrocardiogram (ECG) showed sinus bradycardia, 1st grade atrioventricular block, long corrected QT interval, and Osborn waves at the end of QRS complexes ( <xref ref-type="fig" rid="f01001">Figure 1 A</xref> , arrowheads). Accordingly, these positive notching deflections were best seen in lateral precordial leads and disappeared after warming the patient to 36&#186;C ( <xref ref-type="fig" rid="f01001">Figure 1B</xref> ). The bradycardia, atrioventricular block, and QT prolongation were also resolved ( <xref ref-type="fig" rid="f01001">Figure 1 B</xref> ). During the inward stay, head computed tomography scan, 24-hour Holter, and laboratory analysis were unremarkable for pathological findings. Transthoracic echocardiogram only revealed degenerative aortic and mitral valve changes. This case is illustrative of hypothermia-induced electrocardiographic changes, namely prolongation of the PR, RR and QT intervals and particularly the presence of Osborn Waves.<sup><xref ref-type="bibr" rid="B1">1</xref> , <xref ref-type="bibr" rid="B2">2</xref></sup></p>
      <p>
        <fig id="f01001">
          <label>Figure 1</label>
          <caption>
            <title>&#8211; <italic>Panel A) Electrocardiogram (ECG) showing hypothermia-induced ECG changes: sinus bradycardia, 1st grade atrioventricular block, long corrected QT interval, and Osborn waves at the end of QRS complexes (arrowheads). Panel B) The ECG after warming the patient showing resolution of hypothermia-induced ECG changes.</italic></title>
          </caption>
          <graphic xlink:href="1678-4170-abc-114-06-1076-00081-gf01-en.jpg"/></fig>
      </p>
    </body>
  </sub-article>
</article>
