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  <front>
    <journal-meta>
      <journal-id journal-id-type="nlm-ta">Arq. Bras. Cardiol.</journal-id>
      <journal-title-group>
        <journal-title>Arquivos Brasileiros de Cardiologia</journal-title>
        <abbrev-journal-title abbrev-type="publisher">Arq. Bras. Cardiol.</abbrev-journal-title>
      </journal-title-group>
      <issn pub-type="ppub">0066-782X</issn>
      <issn pub-type="epub">1678-4170</issn>
      <publisher>
        <publisher-name>Sociedade Brasileira de Cardiologia</publisher-name>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id" specific-use="scielo-v3">9DxZJrSCzMqt37kg9L8qMFf</article-id>
      <article-id pub-id-type="publisher-id" specific-use="scielo-v2">S0066-782X2014000100020</article-id>
      <article-id pub-id-type="other">0020</article-id>
      <article-id pub-id-type="doi">10.5935/abc.20130247</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Imagem</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title xml:lang="pt">Endocardite Infecciosa Fatal em Paciente em Terapia de
               Ressincroniza&#231;&#227;o Card&#237;aca</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <name>
            <surname>Fabregat-Andr&#233;s</surname>
            <given-names>Oscar</given-names>
          </name>
          <xref ref-type="corresp" rid="c01"/>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Bochard-Villanueva</surname>
            <given-names>Bruno</given-names>
          </name>
        </contrib>
        <aff>
          <institution content-type="orgname">Hospital General Universitario de
                  Valencia</institution>
          <institution content-type="original">Hospital General Universitario de Valencia,
                  Espanha</institution>
          <country>Espanha</country>
        </aff>
      </contrib-group>
      <author-notes>
        <corresp id="c01"><bold>Correspond&#234;ncia: &#211;scar Fabregat Andr&#233;s</bold>, Av. Tres Cruces, 2, Valencia.
               C&#243;digo postal 46014, Valencia, Espanha. E-mail: <email>haskarande@gmail.com</email>,
                  <email>osfan@comv.es</email>
				</corresp>
        <fn fn-type="conflict">
          <p>
            <bold>Potencial Conflito de Interesses</bold>
          </p>
          <p>Declaro n&#227;o haver conflito de interesses pertinentes.</p>
        </fn>
      </author-notes>
      <pub-date pub-type="epub-ppub">
        <month>1</month>
        <year>2014</year>
      </pub-date>
      <volume>102</volume>
      <issue>1</issue>
      <elocation-id>e9</elocation-id>
      <history>
        <date date-type="received">
          <day>23</day>
          <month>04</month>
          <year>2013</year>
        </date>
        <date date-type="rev-recd">
          <day>24</day>
          <month>04</month>
          <year>2013</year>
        </date>
        <date date-type="accepted">
          <day>26</day>
          <month>04</month>
          <year>2013</year>
        </date>
      </history>
      <permissions>
        <license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by-nc/3.0/">
          <license-p>This is an Open Access article distributed under the terms of the Creative
                  Commons Attribution Non-Commercial License which permits unrestricted
                  non-commercial use, distribution, and reproduction in any medium, provided the
                  original work is properly cited. </license-p>
        </license>
      </permissions>
      <kwd-group xml:lang="pt">
        <kwd>Endocardite infecciosa</kwd>
        <kwd>Ressincroniza&#231;&#227;o card&#237;aca</kwd>
      </kwd-group>
      <counts>
        <fig-count count="1"/>
        <table-count count="0"/>
        <equation-count count="0"/>
        <ref-count count="0"/>
        <page-count count="2"/>
      </counts>
    </article-meta>
  </front>
  <body>
    <p>Homem de 71 anos de idade submetido a terapia de ressincroniza&#231;&#227;o card&#237;aca com implante de
         desfibrilador (TRC-D), h&#225; cinco anos, internado por doen&#231;a febril prolongada.
         Ecocardiograma transtor&#225;cico inicial identificou vegeta&#231;&#227;o &#250;nica de 10 mm aderida aos cabos
         do dispositivo. Antibi&#243;tico triplo foi iniciado com resposta cl&#237;nica favor&#225;vel inicial, mas
         o ecocardiograma transesof&#225;gico de controle (ETE) em dez dias apresentou diversas grandes
         vegeta&#231;&#245;es m&#243;veis aderidas &#224;s deriva&#231;&#245;es do TRC-D, parcialmente ocupando o anel tric&#250;spide
            (<italic>A-B</italic>). ETE tridimensional confirmou esses achados (<italic>C</italic>).
         Consequentemente, uma cirurgia card&#237;aca emergencial foi indicada para a remo&#231;&#227;o do
         dispositivo (<italic>D</italic>). O paciente morreu em 48 horas em virtude de s&#237;ndrome de
         disfun&#231;&#227;o m&#250;ltipla de &#243;rg&#227;os.</p>
    <sec>
      <title>Contribui&#231;&#227;o dos autores</title>
      <p>Concep&#231;&#227;o e desenho da pesquisa, Obten&#231;&#227;o de dados e Revis&#227;o cr&#237;tica do manuscrito
            quanto ao conte&#250;do intelectual: Fabregat-Andr&#233;s O, Bochard-Villanueva B; Reda&#231;&#227;o do
            manuscrito: Fabregat-Andr&#233;s O. </p>
      <fig id="f01" fig-type="other">
        <label>Figura 1</label>
        <caption>
          <title>Endocardite infecciosa relacionada &#224; terapia de ressincroniza&#231;&#227;o card&#237;aca
                  (A-B) Ecocardiograma transesof&#225;gico bidimensional (ETE) mostrando a vegeta&#231;&#227;o
                  gigante aderida &#225;s deriva&#231;&#245;es do dispositivo (seta vermelha). (C) ETE
                  tridimensional mostrando a orienta&#231;&#227;o espacial da massa no anel tric&#250;spide. (D)
                  Imagem da amostra cir&#250;rgica. AD: &#225;trio direito. VD: ventr&#237;culo direito. AE: &#225;trio
                  esquerdo.</title>
        </caption>
        <graphic xlink:href="1678-4170-abc-102-01-00e9-30247-gf01.jpg"/></fig>
      <supplementary-material id="s01">
        <label>V&#237;deo 1</label>
        <caption>
          <p>Ecocardiograma transesof&#225;gico bidimensional mostrando diversas grandes vegeta&#231;&#245;es
                  m&#243;veis aderidas &#224;s deriva&#231;&#245;es do dispositivo e ocupando parcialmente o anel
                  tric&#250;spide.</p>
        </caption>
        <media xlink:href="" mimetype="video" mime-subtype="mp4"/>
      </supplementary-material>
      <supplementary-material id="s02">
        <label>V&#237;deo 2</label>
        <caption>
          <p>Ecocardiograma transesof&#225;gico tridimensional confirmou a orienta&#231;&#227;o espacial da
                  massa gigante.</p>
        </caption>
        <media xlink:href="" mimetype="video" mime-subtype="mp4"/>
      </supplementary-material>
    </sec>
  </body>
  <back>
    <fn-group>
      <fn fn-type="other">
        <p>
          <bold>Vincula&#231;&#227;o Acad&#234;mica</bold>
        </p>
        <p>N&#227;o h&#225; vincula&#231;&#227;o deste estudo com disserta&#231;&#245;es e teses de p&#243;s-gradua&#231;&#227;o.</p>
      </fn>
      <fn fn-type="financial-disclosure">
        <p>
          <bold>Fontes de Financiamento</bold>
        </p>
        <p>O presente estudo n&#227;o teve fontes de financiamento externas.</p>
      </fn>
    </fn-group>
  </back>
  <sub-article id="SA1" article-type="translation" xml:lang="en">
    <front-stub>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Image</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title xml:lang="en">Fatal Infective Endocarditis in a Patient with Cardiac
               Resynchronization Therapy</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <name>
            <surname>Fabregat-Andr&#233;s</surname>
            <given-names>Oscar</given-names>
          </name>
          <xref ref-type="corresp" rid="c02"/>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Bochard-Villanueva</surname>
            <given-names>Bruno</given-names>
          </name>
        </contrib>
        <aff>
          <institution content-type="orgname">Hospital General Universitario de
                  Valencia</institution>
          <country>Spain</country>
          <institution content-type="original">Hospital General Universitario de Valencia,
                  Spain</institution>
        </aff>
      </contrib-group>
      <author-notes>
        <corresp id="c02"><bold>Mailing Address: &#211;scar Fabregat Andr&#233;s</bold>, Av. Tres Cruces, 2, Valencia.
               Postal Code 46014, Valencia, Spain. E-mail: <email>haskarande@gmail.com</email>,
                  <email>osfan@comv.es</email></corresp>
        <fn fn-type="conflict">
          <p>
            <bold>Potential Conflict of Interest</bold>
          </p>
          <p>No potential conflict of interest relevant to this article was reported.</p>
        </fn>
      </author-notes>
      <kwd-group xml:lang="en">
        <kwd>Infective endocarditis</kwd>
        <kwd>Cardiac resynchronization</kwd>
      </kwd-group>
      <counts>
        <fig-count count="1"/>
        <table-count count="0"/>
        <equation-count count="0"/>
        <ref-count count="0"/>
        <page-count count="2"/>
      </counts>
    </front-stub>
    <body>
      <p>A 71-year-old man who underwent cardiac resynchronization therapy with a defibrillator
            (CRT-D) implantation five years ago, was admitted by a lengthy febrile illness. An
            initial transthoracic echocardiogram identified a unique vegetation of 10 mm adhered to
            device cables. Triple antibiotic was started with initial favorable clinical response,
            but the control transesophageal echocardiogram (TEE) at ten days showed several large
            mobile vegetations adhered to CRT-D leads and partially occupying the tricuspid annulus
            (A-B). Three-dimensional TEE confirmed these findings (C). Accordingly, emergent cardiac
            surgery for device removal was indicated (D). The patient died within 48 hours because
            of septic multiple organ dysfunction syndrome.</p>
      <sec>
        <title>Author contributions</title>
        <p>Conception and design of the research, Acquisition of data and Critical revision of
               the manuscript for intellectual content: Fabregat-Andr&#233;s O, Bochard-Villanueva B;
               Writing of the manuscript: Fabregat-Andr&#233;s O.</p>
        <fig id="f02" fig-type="other">
          <label>Figure 1</label>
          <caption>
            <title>Infective endocarditis related to cardiac resynchronization therapy. (A-B)
                     Two-dimensional transesophageal echocardiography (TEE) showing the giant
                     vegetation adhered to device leads (red arrow). (C) Three-dimensional TEE
                     showing the spatial orientation of the mass in the tricuspid annulus. (D)
                     Picture of the surgical specimen. RA: right atrium. RV: right ventricle. LA:
                     left atrium.</title>
          </caption>
          <graphic xlink:href="1678-4170-abc-102-01-00e9-30247-gf01-en.jpg"/></fig>
        <supplementary-material id="s03">
          <label>Video 1</label>
          <caption>
            <p>Two-dimensional transesophageal echocardiogram showing several large mobile
                     vegetations adhered to device leads and partially occupying the tricuspid
                     annulus.</p>
          </caption>
          <media xlink:href="" mimetype="video" mime-subtype="mp4"/>
        </supplementary-material>
        <supplementary-material id="s04">
          <label>Video 2</label>
          <caption>
            <p>Three-dimensional transesophageal echocardiogram confirmed the spatial
                     orientation of the giant mass.</p>
          </caption>
          <media xlink:href="" mimetype="video" mime-subtype="mp4"/>
        </supplementary-material>
      </sec>
    </body>
    <back>
      <fn-group>
        <fn fn-type="other">
          <p>
            <bold>Study Association</bold>
          </p>
          <p>This study is not associated with any thesis or dissertation work.</p>
        </fn>
        <fn fn-type="financial-disclosure">
          <p>
            <bold>Sources of Funding</bold>
          </p>
          <p>There were no external funding sources for this study.</p>
        </fn>
      </fn-group>
    </back>
  </sub-article>
</article>
